Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice

Cervical cancer (CC) is usually initiated by infection with high‐risk types of human papillomavirus (HPV). The HPV E6 and E7 proteins target p53 and RB, respectively, but other cellular targets likely exist. We generated uterus‐specific MOB1A/B double KO (uMob1DKO) mice, which immediately developed...

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Detaylı Bibliyografya
Yayımlandı:Cancer Sci
Asıl Yazarlar: Nishio, Miki, To, Yoko, Maehama, Tomohiko, Aono, Yukari, Otani, Junji, Hikasa, Hiroki, Kitagawa, Akihiro, Mimori, Koshi, Sasaki, Takehiko, Nishina, Hiroshi, Toyokuni, Shinya, Lydon, John P., Nakao, Kazuwa, Wah Mak, Tak, Kiyono, Tohru, Katabuchi, Hidetaka, Tashiro, Hironori, Suzuki, Akira
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Carcinogenesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541006/
https://ncbi.nlm.nih.gov/pubmed/32716083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14581
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