Hypertonic saline mediates the NLRP3/IL‐1β signaling axis in microglia to alleviate ischemic blood‐brain barrier permeability by downregulating astrocyte‐derived VEGF in rats

INTRODUCTION: The aim of this study was to explore whether the antibrain edema of hypertonic saline (HS) is associated with alleviating ischemic blood‐brain barrier (BBB) permeability by downregulating astrocyte‐derived vascular endothelial growth factor (VEGF), which is mediated by microglia‐derive...

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Bibliografiske detaljer
Udgivet i:CNS Neurosci Ther
Main Authors: Wang, Qiao‐sheng, Ding, Hong‐guang, Chen, Sheng‐long, Liu, Xin‐qiang, Deng, Yi‐yu, Jiang, Wen‐qiang, Li, Ya, Huang, Lin‐qiang, Han, Yong‐li, Wen, Miao‐yun, Wang, Mei‐qiu, Zeng, Hong‐ke
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539845/
https://ncbi.nlm.nih.gov/pubmed/32529750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13427
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