Procyanidins alleviates morphine tolerance by inhibiting activation of NLRP3 inflammasome in microglia

BACKGROUND: The development of antinociceptive tolerance following repetitive administration of opioid analgesics significantly hinders their clinical use. Evidence has accumulated indicating that microglia within the spinal cord plays a critical role in morphine tolerance. The inhibitor of microgli...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Cai, Yang, Kong, Hong, Pan, Yin-Bing, Jiang, Lai, Pan, Xiu-Xiu, Hu, Liang, Qian, Yan-Ning, Jiang, Chun-Yi, Liu, Wen-Tao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774188/
https://ncbi.nlm.nih.gov/pubmed/26931361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0520-z
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi