Hypertonic saline attenuates expression of Notch signaling and proinflammatory mediators in activated microglia in experimentally induced cerebral ischemia and hypoxic BV-2 microglia

BACKGROUND: Ischemic stroke is a major disease that threatens human health in ageing population. Increasing evidence has shown that neuroinflammatory mediators play crucial roles in the pathophysiology of cerebral ischemia injury. Notch signaling is recognized as the cell fate signaling but recent e...

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Dettagli Bibliografici
Pubblicato in:BMC Neurosci
Autori principali: Zeng, Wen-Xin, Han, Yong-Li, Zhu, Gao-Feng, Huang, Lin-Qiang, Deng, Yi-Yu, Wang, Qiao-Sheng, Jiang, Wen-Qiang, Wen, Miao-Yun, Han, Qian-Peng, Xie, Di, Zeng, Hong-Ke
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348816/
https://ncbi.nlm.nih.gov/pubmed/28288585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-017-0351-6
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