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Hypertonic saline attenuates expression of Notch signaling and proinflammatory mediators in activated microglia in experimentally induced cerebral ischemia and hypoxic BV-2 microglia

BACKGROUND: Ischemic stroke is a major disease that threatens human health in ageing population. Increasing evidence has shown that neuroinflammatory mediators play crucial roles in the pathophysiology of cerebral ischemia injury. Notch signaling is recognized as the cell fate signaling but recent e...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: Zeng, Wen-Xin, Han, Yong-Li, Zhu, Gao-Feng, Huang, Lin-Qiang, Deng, Yi-Yu, Wang, Qiao-Sheng, Jiang, Wen-Qiang, Wen, Miao-Yun, Han, Qian-Peng, Xie, Di, Zeng, Hong-Ke
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348816/
https://ncbi.nlm.nih.gov/pubmed/28288585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-017-0351-6
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