Somatic mutation profiling in BRCA-negative breast and ovarian cancer patients by multigene panel sequencing

Targeted therapeutic agents such as poly (ADP-ribose) polymerases (PARP) inhibitors have emerged in treating cancers associated with germline BRCA mutations. Recently studies demonstrated the effectiveness of PARP inhibitors in treating patients with somatic BRCA mutations. Somatic mutations in 122...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Kwong, Ava, Cheuk, Isabella WY, Shin, Vivian Yvonne, Ho, Cecilia YS, Au, Chun-Hang, Ho, Dona NY, Wong, Elaine YL, Yu, Stephanie WY, Chen, Jiawei, Chan, Karen KL, Ngan, Hextan YS, Chan, Tsun-Leung, Ma, Edmond SK
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539773/
https://ncbi.nlm.nih.gov/pubmed/33042626
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