Rapid detection of BRCA1/2 recurrent mutations in Chinese breast and ovarian cancer patients with multiplex SNaPshot genotyping panels

BRCA1/2 mutations are significant risk factors for hereditary breast and ovarian cancer (HBOC), its mutation frequency in HBOC of Chinese ethnicity is around 9%, in which nearly half are recurrent mutations. In Hong Kong and China, genetic testing and counseling are not as common as in the West. To...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Kwong, Ava, Ho, John C.W., Shin, Vivian Y., Kurian, Allison W., Tai, Edmund, Esserman, Laura J., Weitzel, Jeffery N., Lin, Po-Han, Field, Michael, Domchek, Susan M., Lo, Jessica, Ngan, Hextan Y.S., Ma, Edmond S.K., Chan, Tsun L., Ford, James M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814262/
https://ncbi.nlm.nih.gov/pubmed/29487695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23471
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