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BAMClipper: removing primers from alignments to minimize false-negative mutations in amplicon next-generation sequencing
Amplicon-based next-generation sequencing (NGS) has been widely adopted for genetic variation detection in human and other organisms. Conventional data analysis paradigm includes primer trimming before read mapping. Here we introduce BAMClipper that removes primer sequences after mapping original se...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5431517/ https://ncbi.nlm.nih.gov/pubmed/28484262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01703-6 |
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