Somatic mutation profiling in BRCA-negative breast and ovarian cancer patients by multigene panel sequencing

Targeted therapeutic agents such as poly (ADP-ribose) polymerases (PARP) inhibitors have emerged in treating cancers associated with germline BRCA mutations. Recently studies demonstrated the effectiveness of PARP inhibitors in treating patients with somatic BRCA mutations. Somatic mutations in 122...

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Vydáno v:Am J Cancer Res
Hlavní autoři: Kwong, Ava, Cheuk, Isabella WY, Shin, Vivian Yvonne, Ho, Cecilia YS, Au, Chun-Hang, Ho, Dona NY, Wong, Elaine YL, Yu, Stephanie WY, Chen, Jiawei, Chan, Karen KL, Ngan, Hextan YS, Chan, Tsun-Leung, Ma, Edmond SK
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539773/
https://ncbi.nlm.nih.gov/pubmed/33042626
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