Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry

The Consortium for Top-Down Proteomics (www.topdownproteomics.org) launched the present study to assess the current state of top-down mass spectrometry (TD MS) and middle-down mass spectrometry (MD MS) for characterizing monoclonal antibody (mAb) primary structures, including their modifications. To...

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Publicado en:J Am Soc Mass Spectrom
Autores principales: Srzentić, Kristina, Fornelli, Luca, Tsybin, Yury O., Loo, Joseph A., Seckler, Henrique, Agar, Jeffrey N., Anderson, Lissa C., Bai, Dina L., Beck, Alain, Brodbelt, Jennifer S., van der Burgt, Yuri E. M., Chamot-Rooke, Julia, Chatterjee, Sneha, Chen, Yunqiu, Clarke, David J., Danis, Paul O., Diedrich, Jolene K., D’Ippolito, Robert A., Dupré, Mathieu, Gasilova, Natalia, Ge, Ying, Goo, Young Ah, Goodlett, David R., Greer, Sylvester, Haselmann, Kim F., He, Lidong, Hendrickson, Christopher L., Hinkle, Joshua D., Holt, Matthew V., Hughes, Sam, Hunt, Donald F., Kelleher, Neil L., Kozhinov, Anton N., Lin, Ziqing, Malosse, Christian, Marshall, Alan G., Menin, Laure, Millikin, Robert J., Nagornov, Konstantin O., Nicolardi, Simone, Paša-Tolić, Ljiljana, Pengelley, Stuart, Quebbemann, Neil R., Resemann, Anja, Sandoval, Wendy, Sarin, Richa, Schmitt, Nicholas D., Shabanowitz, Jeffrey, Shaw, Jared B., Shortreed, Michael R., Smith, Lloyd M., Sobott, Frank, Suckau, Detlev, Toby, Timothy, Weisbrod, Chad R., Wildburger, Norelle C., Yates, John R., Yoon, Sung Hwan, Young, Nicolas L., Zhou, Mowei
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539639/
https://ncbi.nlm.nih.gov/pubmed/32812765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jasms.0c00036
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