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Fast QC of Intact Monoclonal Antibodies Using MALDI-Top-Down Sequencing
Antibodies are playing an important role in drug development in the last years. The function of therapeutic monoclonal antibodies (mAbs) is directly depending on their structure including terminal modifications like C-terminal lysine excision and N-terminal pyroglutamylation of the heavy chain. Here...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Association of Biomolecular Resource Facilities
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3186624/ |
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