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P145-S Interactive and Automated Top-Down Analysis of Sequencing Data of Intact Proteins
In a Top-Down workflow (ECD, ETD, ISD) the whole protein molecule is subjected to fragmentation and proteins are not digested (as in the Bottom-Up approach). This allows the detection of signal peptides, modifications, sequence variations and mutations. Top-Down analyses can be done using FTMS/ECD/E...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Association of Biomolecular Resource Facilities
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291934/ |
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