Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry

The Consortium for Top-Down Proteomics (www.topdownproteomics.org) launched the present study to assess the current state of top-down mass spectrometry (TD MS) and middle-down mass spectrometry (MD MS) for characterizing monoclonal antibody (mAb) primary structures, including their modifications. To...

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Veröffentlicht in:J Am Soc Mass Spectrom
Hauptverfasser: Srzentić, Kristina, Fornelli, Luca, Tsybin, Yury O., Loo, Joseph A., Seckler, Henrique, Agar, Jeffrey N., Anderson, Lissa C., Bai, Dina L., Beck, Alain, Brodbelt, Jennifer S., van der Burgt, Yuri E. M., Chamot-Rooke, Julia, Chatterjee, Sneha, Chen, Yunqiu, Clarke, David J., Danis, Paul O., Diedrich, Jolene K., D’Ippolito, Robert A., Dupré, Mathieu, Gasilova, Natalia, Ge, Ying, Goo, Young Ah, Goodlett, David R., Greer, Sylvester, Haselmann, Kim F., He, Lidong, Hendrickson, Christopher L., Hinkle, Joshua D., Holt, Matthew V., Hughes, Sam, Hunt, Donald F., Kelleher, Neil L., Kozhinov, Anton N., Lin, Ziqing, Malosse, Christian, Marshall, Alan G., Menin, Laure, Millikin, Robert J., Nagornov, Konstantin O., Nicolardi, Simone, Paša-Tolić, Ljiljana, Pengelley, Stuart, Quebbemann, Neil R., Resemann, Anja, Sandoval, Wendy, Sarin, Richa, Schmitt, Nicholas D., Shabanowitz, Jeffrey, Shaw, Jared B., Shortreed, Michael R., Smith, Lloyd M., Sobott, Frank, Suckau, Detlev, Toby, Timothy, Weisbrod, Chad R., Wildburger, Norelle C., Yates, John R., Yoon, Sung Hwan, Young, Nicolas L., Zhou, Mowei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539639/
https://ncbi.nlm.nih.gov/pubmed/32812765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jasms.0c00036
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