Zinc inhibits lethal inflammatory shock by preventing microbe‐induced interferon signature in intestinal epithelium

The cytokine TNF drives inflammatory diseases, e.g., Crohn's disease. In a mouse model of TNF‐induced systemic inflammatory response syndrome (SIRS), severe impact on intestinal epithelial cells (IECs) is observed. Zinc confers complete protection in this model. We found that zinc no longer pro...

詳細記述

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出版年:EMBO Mol Med
主要な著者: Souffriau, Jolien, Timmermans, Steven, Vanderhaeghen, Tineke, Wallaeys, Charlotte, Van Looveren, Kelly, Aelbrecht, Lindsy, Dewaele, Sylviane, Vandewalle, Jolien, Goossens, Evy, Verbanck, Serge, Boyen, Filip, Eggermont, Melanie, De Commer, Lindsey, De Rycke, Riet, De Bruyne, Michiel, Tito, Raul, Ballegeer, Marlies, Vandevyver, Sofie, Velho, Tiago, Moita, Luis Ferreira, Hochepied, Tino, De Bosscher, Karolien, Raes, Jeroen, Van Immerseel, Filip, Beyaert, Rudi, Libert, Claude
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539219/
https://ncbi.nlm.nih.gov/pubmed/32914580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201911917
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