A screening assay for Selective Dimerizing Glucocorticoid Receptor Agonists and Modulators (SEDIGRAM) that are effective against acute inflammation

It has been suggested that glucocorticoid receptor (GR) agonists that promote GR homodimerization more than standard glucocorticoids such as Dexamethasone could be more effective anti-inflammatory molecules against acute and life-threatening inflammatory conditions. To test this hypothesis, we set u...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Souffriau, Jolien, Eggermont, Melanie, Van Ryckeghem, Sara, Van Looveren, Kelly, Van Wyngene, Lise, Van Hamme, Evelien, Vuylsteke, Marnik, Beyaert, Rudi, De Bosscher, Karolien, Libert, Claude
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110732/
https://ncbi.nlm.nih.gov/pubmed/30150712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31150-w
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