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Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice
TNF is an important mediator in numerous inflammatory diseases, e.g., in inflammatory bowel diseases (IBDs). In IBD, acute increases in TNF production can lead to disease flares. Glucocorticoids (GCs), which are steroids that bind and activate the glucocorticoid receptor (GR), are able to protect an...
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| I publikationen: | J Clin Invest |
|---|---|
| Huvudupphovsmän: | , , , , , , , , , , , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Clinical Investigation
2018
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6063488/ https://ncbi.nlm.nih.gov/pubmed/29746256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96636 |
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