Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice

TNF is an important mediator in numerous inflammatory diseases, e.g., in inflammatory bowel diseases (IBDs). In IBD, acute increases in TNF production can lead to disease flares. Glucocorticoids (GCs), which are steroids that bind and activate the glucocorticoid receptor (GR), are able to protect an...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Ballegeer, Marlies, Van Looveren, Kelly, Timmermans, Steven, Eggermont, Melanie, Vandevyver, Sofie, Thery, Fabien, Dendoncker, Karen, Souffriau, Jolien, Vandewalle, Jolien, Van Wyngene, Lise, De Rycke, Riet, Takahashi, Nozomi, Vandenabeele, Peter, Tuckermann, Jan, Reichardt, Holger M., Impens, Francis, Beyaert, Rudi, De Bosscher, Karolien, Vandenbroucke, Roosmarijn E., Libert, Claude
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063488/
https://ncbi.nlm.nih.gov/pubmed/29746256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96636
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