TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile

Glucocorticoid resistance (GCR) is defined as an unresponsiveness to the therapeutic effects, including the antiinflammatory ones of glucocorticoids (GCs) and their receptor, the glucocorticoid receptor (GR). It is a problem in the management of inflammatory diseases and can be congenital as well as...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Dendoncker, Karen, Timmermans, Steven, Vandewalle, Jolien, Eggermont, Melanie, Lempiäinen, Joanna, Van Hamme, Evelien, Dewaele, Sylviane, Vandevyver, Sofie, Ballegeer, Marlies, Souffriau, Jolien, Van Wyngene, Lise, Van Looveren, Kelly, Vanderhaeghen, Tineke, Beyaert, Rudi, De Bosscher, Karolien, Palvimo, Jorma J., Van Montagu, Marc, Libert, Claude
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600915/
https://ncbi.nlm.nih.gov/pubmed/31182584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821565116
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi