A screening assay for Selective Dimerizing Glucocorticoid Receptor Agonists and Modulators (SEDIGRAM) that are effective against acute inflammation

It has been suggested that glucocorticoid receptor (GR) agonists that promote GR homodimerization more than standard glucocorticoids such as Dexamethasone could be more effective anti-inflammatory molecules against acute and life-threatening inflammatory conditions. To test this hypothesis, we set u...

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發表在:Sci Rep
Main Authors: Souffriau, Jolien, Eggermont, Melanie, Van Ryckeghem, Sara, Van Looveren, Kelly, Van Wyngene, Lise, Van Hamme, Evelien, Vuylsteke, Marnik, Beyaert, Rudi, De Bosscher, Karolien, Libert, Claude
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110732/
https://ncbi.nlm.nih.gov/pubmed/30150712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31150-w
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