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RNA oxidation in chromatin modification and DNA-damage response following exposure to formaldehyde

Formaldehyde is an environmental and occupational chemical carcinogen implicated in the damage of proteins and nucleic acids. However, whether formaldehyde provokes modifications of RNAs such as 8-oxo-7,8-dihydroguanine (8-oxoG) and the role that these modifications play on conferring long-term adve...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Gonzalez-Rivera, Juan C., Sherman, Mark W., Wang, Dongyu S., Chuvalo-Abraham, Jamie C. L., Hildebrandt Ruiz, Lea, Contreras, Lydia M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7538935/
https://ncbi.nlm.nih.gov/pubmed/33024153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73376-7
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