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RNA oxidation in chromatin modification and DNA-damage response following exposure to formaldehyde

Formaldehyde is an environmental and occupational chemical carcinogen implicated in the damage of proteins and nucleic acids. However, whether formaldehyde provokes modifications of RNAs such as 8-oxo-7,8-dihydroguanine (8-oxoG) and the role that these modifications play on conferring long-term adve...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gonzalez-Rivera, Juan C., Sherman, Mark W., Wang, Dongyu S., Chuvalo-Abraham, Jamie C. L., Hildebrandt Ruiz, Lea, Contreras, Lydia M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7538935/
https://ncbi.nlm.nih.gov/pubmed/33024153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73376-7
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