Immunization with Mycobacterium tuberculosis–Specific Antigens Bypasses T Cell Differentiation from Prior Bacillus Calmette–Guérin Vaccination and Improves Protection in Mice

Despite the fact that the majority of people in tuberculosis (TB)–endemic areas are vaccinated with the Bacillus Calmette–Guérin (BCG) vaccine, TB remains the leading infectious cause of death. Data from both animal models and humans show that BCG and subunit vaccines induce T cells of different phe...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Aagaard, Claus, Knudsen, Niels Peter Hell, Sohn, Iben, Izzo, Angelo A., Kim, Hongmin, Kristiansen, Emma Holsey, Lindenstrøm, Thomas, Agger, Else Marie, Rasmussen, Michael, Shin, Sung Jae, Rosenkrands, Ida, Andersen, Peter, Mortensen, Rasmus
Format: Artigo
Sprache:Inglês
Veröffentlicht: AAI 2020
Schlagworte:
Immunotherapy and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533711/
https://ncbi.nlm.nih.gov/pubmed/32887748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000563
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge