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High-frequency vaccine-induced CD8(+) T cells specific for an epitope naturally processed during infection with M. tuberculosis do not confer protection
Relatively few MHC class I epitopes have been identified from M. tuberculosis, but during the late stage of infection CD8(+) T-cell responses to these epitopes are often primed at an extraordinary high frequency. Although clearly available for recognition during infection, their role in resistance t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4112357/ https://ncbi.nlm.nih.gov/pubmed/24677089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344358 |
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