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T Cells Primed by Live Mycobacteria Versus a Tuberculosis Subunit Vaccine Exhibit Distinct Functional Properties

Despite inducing strong T cell responses, Mycobacterium tuberculosis (Mtb) infection fails to elicit protective immune memory. As such latently infected or successfully treated Tuberculosis (TB) patients are not protected against recurrent disease. Here, using a mouse model of aerosol Mtb infection,...

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Bibliografiske detaljer
Udgivet i:EBioMedicine
Main Authors: Lindenstrøm, Thomas, Moguche, Albanus, Damborg, Mie, Agger, Else Marie, Urdahl, Kevin, Andersen, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828549/
https://ncbi.nlm.nih.gov/pubmed/29249639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.12.004
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