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Adjuvant modulation of the cytokine balance in Mycobacterium tuberculosis subunit vaccines; immunity, pathology and protection

It is known that protection against tuberculosis is mediated primarily by T helper type 1 (Th1) cells but the influence of the Th1/Th2 balance of a vaccination response on the subsequent protection and pathology during infection has not been studied in detail. We designed a panel of Ag85B-ESAT-6 sub...

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Detalhes bibliográficos
Main Authors: Agger, Else Marie, Cassidy, Joseph P, Brady, Joseph, Korsholm, Karen S, Vingsbo-Lundberg, Carina, Andersen, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566622/
https://ncbi.nlm.nih.gov/pubmed/18201185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02751.x
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