ESAT-6 (EsxA) and TB10.4 (EsxH) Based Vaccines for Pre- and Post-Exposure Tuberculosis Vaccination

The ESX systems from Mycobacterium tuberculosis are responsible for the secretion of highly immunogenic proteins of key importance for bacterial survival and growth. The two prototypic proteins, ESAT-6 (EsxA from ESX-1) and TB10.4 (EsxH from ESX-3) share a lot of characteristics regarding genome org...

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Detalhes bibliográficos
Main Authors: Hoang, Truc, Aagaard, Claus, Dietrich, Jes, Cassidy, Joseph P., Dolganov, Gregory, Schoolnik, Gary K., Lundberg, Carina Vingsbo, Agger, Else Marie, Andersen, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861245/
https://ncbi.nlm.nih.gov/pubmed/24349004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080579
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