Assessment of the Genetic Diversity of Mycobacterium tuberculosis esxA, esxH, and fbpB Genes among Clinical Isolates and Its Implication for the Future Immunization by New Tuberculosis Subunit Vaccines Ag85B-ESAT-6 and Ag85B-TB10.4

The effort to develop a tuberculosis (TB) vaccine more effective than the widely used Bacille Calmette-Guérin (BCG) has led to the development of two novel fusion protein subunit vaccines: Ag85B-ESAT-6 and Ag85B-TB10.4. Studies of these vaccines in animal models have revealed their ability to genera...

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Detalhes bibliográficos
Main Authors: Davila, Jose, Zhang, Lixin, Marrs, Carl F., Durmaz, Riza, Yang, Zhenhua
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896655/
https://ncbi.nlm.nih.gov/pubmed/20617139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/208371
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