Protein Energy Malnutrition during Vaccination Has Limited Influence on Vaccine Efficacy but Abolishes Immunity if Administered during Mycobacterium tuberculosis Infection

Protein energy malnutrition (PEM) increases susceptibility to infectious diseases, including tuberculosis (TB), but it is not clear how PEM influences vaccine-promoted immunity to TB. We demonstrate that PEM during low-level steady-state TB infection in a mouse model results in rapid relapse of Myco...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Hoang, Truc, Agger, Else Marie, Cassidy, Joseph P., Christensen, Jan P., Andersen, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399034/
https://ncbi.nlm.nih.gov/pubmed/25754202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.03030-14
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