Tuberculosis vaccine with high predicted population coverage and compatibility with modern diagnostics

A central goal in vaccine research is the identification of relevant antigens. The Mycobacterium tuberculosis chromosome encodes 23 early secretory antigenic target (ESAT-6) family members that mostly are localized as gene pairs. In proximity to five of the gene pairs are ESX secretion systems invol...

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Detalhes bibliográficos
Main Authors: Knudsen, Niels Peter H., Nørskov-Lauritsen, Sara, Dolganov, Gregory M., Schoolnik, Gary K., Lindenstrøm, Thomas, Andersen, Peter, Agger, Else Marie, Aagaard, Claus
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903227/
https://ncbi.nlm.nih.gov/pubmed/24395772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314973111
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