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Immunization with Mycobacterium tuberculosis–Specific Antigens Bypasses T Cell Differentiation from Prior Bacillus Calmette–Guérin Vaccination and Improves Protection in Mice

Despite the fact that the majority of people in tuberculosis (TB)–endemic areas are vaccinated with the Bacillus Calmette–Guérin (BCG) vaccine, TB remains the leading infectious cause of death. Data from both animal models and humans show that BCG and subunit vaccines induce T cells of different phe...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Aagaard, Claus, Knudsen, Niels Peter Hell, Sohn, Iben, Izzo, Angelo A., Kim, Hongmin, Kristiansen, Emma Holsey, Lindenstrøm, Thomas, Agger, Else Marie, Rasmussen, Michael, Shin, Sung Jae, Rosenkrands, Ida, Andersen, Peter, Mortensen, Rasmus
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533711/
https://ncbi.nlm.nih.gov/pubmed/32887748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000563
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