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The mode of action of the Protein tyrosine phosphatase 1B inhibitor Ertiprotafib
Protein tyrosine phosphatase 1B (PTP1B) is a validated therapeutic target for the treatment of diabetes and obesity. Ertiprotafib is a PTP1B inhibitor that reached the clinical trial stage for the treatment of diabetes. Interestingly, Ertiprotafib reduces the melting temperature of PTP1B in differen...
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| Publicado no: | PLoS One |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7531832/ https://ncbi.nlm.nih.gov/pubmed/33007022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240044 |
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