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Structural insights into mode of actions of novel natural Mycobacterium protein tyrosine phosphatase B inhibitors
BACKGROUND: Tuberculosis has become a major health problem being the second leading cause of death worldwide. Mycobacterium tuberculosis secretes a virulence factor, protein tyrosine phosphatase B (mPTPB) in the cytoplasm of host macrophage which suppresses its natural innate immune response and hel...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046716/ https://ncbi.nlm.nih.gov/pubmed/24564493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-S1-S3 |
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