Structural insights into mode of actions of novel natural Mycobacterium protein tyrosine phosphatase B inhibitors

BACKGROUND: Tuberculosis has become a major health problem being the second leading cause of death worldwide. Mycobacterium tuberculosis secretes a virulence factor, protein tyrosine phosphatase B (mPTPB) in the cytoplasm of host macrophage which suppresses its natural innate immune response and hel...

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Autores principales: Dhanjal, Jaspreet Kaur, Grover, Sonam, Sharma, Sudhanshu, Singh, Ajeet Kumar, Grover, Abhinav
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Proceedings
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046716/
https://ncbi.nlm.nih.gov/pubmed/24564493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-S1-S3
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