Tofacitinib inhibits the development of experimental autoimmune uveitis and reduces the proportions of Th1 but not of Th17 cells

PURPOSE: Tofacitinib is a pan-Janus kinase (JAK) inhibitor that suppresses cytokine signaling and in turn, the cells that participate in inflammatory immunopathogenic processes. We examined the capacity of tofacitinib to inhibit the induction of experimental autoimmune uveitis (EAU) and related immu...

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Bibliografiska uppgifter
I publikationen:Mol Vis
Huvudupphovsmän: Bing, So Jin, Lyu, Cancan, Xu, Biying, Wandu, Wambui S., Hinshaw, Samuel J., Furumoto, Yasuko, Caspi, Rachel R., Gadina, Massimo, Gery, Igal
Materialtyp: Artigo
Språk:Inglês
Publicerad: Molecular Vision 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531779/
https://ncbi.nlm.nih.gov/pubmed/33088168
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