Tofacitinib inhibits the development of experimental autoimmune uveitis and reduces the proportions of Th1 but not of Th17 cells

PURPOSE: Tofacitinib is a pan-Janus kinase (JAK) inhibitor that suppresses cytokine signaling and in turn, the cells that participate in inflammatory immunopathogenic processes. We examined the capacity of tofacitinib to inhibit the induction of experimental autoimmune uveitis (EAU) and related immu...

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Detalhes bibliográficos
Publicado no:Mol Vis
Main Authors: Bing, So Jin, Lyu, Cancan, Xu, Biying, Wandu, Wambui S., Hinshaw, Samuel J., Furumoto, Yasuko, Caspi, Rachel R., Gadina, Massimo, Gery, Igal
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531779/
https://ncbi.nlm.nih.gov/pubmed/33088168
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