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Digoxin Inhibits Induction of Experimental Autoimmune Uveitis in Mice, but Causes Severe Retinal Degeneration

PURPOSE: Digoxin, a major medication for heart disease, was recently reported to have immunosuppressive capacity. Here, we determined the immunosuppressive capacity of digoxin on the development of experimental autoimmune uveitis (EAU) and on related immune responses. METHODS: The B10.A mice were im...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Hinshaw, Samuel J. H., Ogbeifun, Osato, Wandu, Wambui S., Lyu, Cancan, Shi, Guangpu, Li, Yichao, Qian, Haohua, Gery, Igal
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821074/
https://ncbi.nlm.nih.gov/pubmed/27028065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-19040
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