Digoxin Inhibits Induction of Experimental Autoimmune Uveitis in Mice, but Causes Severe Retinal Degeneration

PURPOSE: Digoxin, a major medication for heart disease, was recently reported to have immunosuppressive capacity. Here, we determined the immunosuppressive capacity of digoxin on the development of experimental autoimmune uveitis (EAU) and on related immune responses. METHODS: The B10.A mice were im...

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Veröffentlicht in:Invest Ophthalmol Vis Sci
Hauptverfasser: Hinshaw, Samuel J. H., Ogbeifun, Osato, Wandu, Wambui S., Lyu, Cancan, Shi, Guangpu, Li, Yichao, Qian, Haohua, Gery, Igal
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2016
Schlagworte:
Immunology and Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821074/
https://ncbi.nlm.nih.gov/pubmed/27028065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-19040
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