Exosomal miR‐1255b‐5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial‐to‐mesenchymal transition

Cancer cells undergo epithelial‐to‐mesenchymal transition (EMT) in response to hypoxia. Exosomes produced in tumor microenvironments carry microRNAs (miRNAs) that affect proliferation, metastasis, and EMT. Hypoxic regulation of EMT is associated with telomerase content and stability, but the underly...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Zhang, Xue, Bai, Jian, Yin, Hang, Long, Long, Zheng, Zhewen, Wang, Qingqing, Chen, Fengxia, Yu, Xiaoyan, Zhou, Yunfeng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530775/
https://ncbi.nlm.nih.gov/pubmed/32679610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12765
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