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Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis

Telomerase is typically expressed in cellular populations capable of extended replication, such as germ cells, tumor cells, and stem cells, but is also induced in tissue injury, repair and fibrosis. Its catalytic component, telomerase reverse transcriptase (TERT) is induced in lung fibroblasts from...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Liu, Tianju, Yu, Hongfeng, Ding, Lin, Wu, Zhe, Gonzalez De Los Santos, Francina, Liu, Jianhua, Ullenbruch, Matthew, Hu, Biao, Martins, Vanessa, Phan, Sem H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640706/
https://ncbi.nlm.nih.gov/pubmed/26555817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142547
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