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Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis

Telomerase is typically expressed in cellular populations capable of extended replication, such as germ cells, tumor cells, and stem cells, but is also induced in tissue injury, repair and fibrosis. Its catalytic component, telomerase reverse transcriptase (TERT) is induced in lung fibroblasts from...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Tianju, Yu, Hongfeng, Ding, Lin, Wu, Zhe, Gonzalez De Los Santos, Francina, Liu, Jianhua, Ullenbruch, Matthew, Hu, Biao, Martins, Vanessa, Phan, Sem H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640706/
https://ncbi.nlm.nih.gov/pubmed/26555817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142547
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