Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis

Telomerase is typically expressed in cellular populations capable of extended replication, such as germ cells, tumor cells, and stem cells, but is also induced in tissue injury, repair and fibrosis. Its catalytic component, telomerase reverse transcriptase (TERT) is induced in lung fibroblasts from...

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Vydáno v:PLoS One
Hlavní autoři: Liu, Tianju, Yu, Hongfeng, Ding, Lin, Wu, Zhe, Gonzalez De Los Santos, Francina, Liu, Jianhua, Ullenbruch, Matthew, Hu, Biao, Martins, Vanessa, Phan, Sem H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640706/
https://ncbi.nlm.nih.gov/pubmed/26555817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142547
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