Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis

Telomerase is typically expressed in cellular populations capable of extended replication, such as germ cells, tumor cells, and stem cells, but is also induced in tissue injury, repair and fibrosis. Its catalytic component, telomerase reverse transcriptase (TERT) is induced in lung fibroblasts from...

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Опубликовано в: :PLoS One
Главные авторы: Liu, Tianju, Yu, Hongfeng, Ding, Lin, Wu, Zhe, Gonzalez De Los Santos, Francina, Liu, Jianhua, Ullenbruch, Matthew, Hu, Biao, Martins, Vanessa, Phan, Sem H.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640706/
https://ncbi.nlm.nih.gov/pubmed/26555817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142547
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