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Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice

In addition to its well-known expression in the germline and in cells of certain cancers, telomerase activity is induced in lung fibrosis, although its role in this process is unknown. To identify the pathogenetic importance of telomerase in lung fibrosis, we examined the effects of telomerase rever...

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Autors principals: Liu, Tianju, Chung, Myoung Ja, Ullenbruch, Matthew, Yu, Hongfeng, Jin, Hong, Hu, Biao, Choi, Yoon Young, Ishikawa, Fuyuki, Phan, Sem H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075478/
https://ncbi.nlm.nih.gov/pubmed/18008008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32369
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