Reemergence of Hedgehog Mediates Epithelial–Mesenchymal Crosstalk in Pulmonary Fibrosis

Hedgehog signaling plays important roles in cell development and differentiation. In this study, the ability of Sonic Hedgehog (SHH) to induce myofibroblast differentiation was analyzed in isolated human lung fibroblasts, and its in vivo significance was evaluated in rodent bleomycin-induced pulmona...

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Publicado en:Am J Respir Cell Mol Biol
Autores principales: Hu, Biao, Liu, Jianhua, Wu, Zhe, Liu, Tianju, Ullenbruch, Matthew R., Ding, Lin, Henke, Craig A., Bitterman, Peter B., Phan, Sem H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2015
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491120/
https://ncbi.nlm.nih.gov/pubmed/25140582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0108OC
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