Reemergence of Hedgehog Mediates Epithelial–Mesenchymal Crosstalk in Pulmonary Fibrosis

Hedgehog signaling plays important roles in cell development and differentiation. In this study, the ability of Sonic Hedgehog (SHH) to induce myofibroblast differentiation was analyzed in isolated human lung fibroblasts, and its in vivo significance was evaluated in rodent bleomycin-induced pulmona...

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Dades bibliogràfiques
Publicat a:Am J Respir Cell Mol Biol
Autors principals: Hu, Biao, Liu, Jianhua, Wu, Zhe, Liu, Tianju, Ullenbruch, Matthew R., Ding, Lin, Henke, Craig A., Bitterman, Peter B., Phan, Sem H.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491120/
https://ncbi.nlm.nih.gov/pubmed/25140582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0108OC
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