Exosomal miR‐1255b‐5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial‐to‐mesenchymal transition

Cancer cells undergo epithelial‐to‐mesenchymal transition (EMT) in response to hypoxia. Exosomes produced in tumor microenvironments carry microRNAs (miRNAs) that affect proliferation, metastasis, and EMT. Hypoxic regulation of EMT is associated with telomerase content and stability, but the underly...

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Bibliografiska uppgifter
I publikationen:Mol Oncol
Huvudupphovsmän: Zhang, Xue, Bai, Jian, Yin, Hang, Long, Long, Zheng, Zhewen, Wang, Qingqing, Chen, Fengxia, Yu, Xiaoyan, Zhou, Yunfeng
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2020
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530775/
https://ncbi.nlm.nih.gov/pubmed/32679610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12765
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