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PD-1 Regulates GABAergic Neurotransmission and GABA-Mediated Analgesia and Anesthesia
The immune checkpoint inhibitor programmed cell death protein 1 (PD-1) plays a critical role in immune regulation. Recent studies have demonstrated functional PD-1 expression in peripheral sensory neurons, which contributes to neuronal excitability, pain, and opioid analgesia. Here we report neurona...
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| Veröffentlicht in: | iScience |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7530307/ https://ncbi.nlm.nih.gov/pubmed/33083737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101570 |
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