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GABAergic Neurotransmission in the Pontine Reticular Formation Modulates Hypnosis, Immobility, and Breathing during Isoflurane Anesthesia

BACKGROUND: Many general anesthetics are thought to produce a loss of wakefulness, in part, by enhancing gamma-aminobutyric acid (GABA) neurotransmission. However, GABAergic neurotransmission in the pontine reticular formation promotes wakefulness. This study tested the hypotheses that: 1) relative...

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Main Authors: Vanini, Giancarlo, Watson, Christopher J., Lydic, Ralph, Baghdoyan, Helen A.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743234/
https://ncbi.nlm.nih.gov/pubmed/19034094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31818e3b1b
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