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Adenosine A(1) Receptors in Mouse Pontine Reticular Formation Depress Breathing, Increase Anesthesia Recovery Time, and Decrease Acetylcholine Release

BACKGROUND: Clinical and preclinical data demonstrate the analgesic actions of adenosine. Central administration of adenosine agonists, however, suppresses arousal and breathing by poorly understood mechanisms. This study tested the two-tailed hypothesis that adenosine A(1) receptors in the pontine...

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Detalhes bibliográficos
Main Authors: Gettys, George C., Liu, Fang, Kimlin, Ed, Baghdoyan, Helen A., Lydic, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553235/
https://ncbi.nlm.nih.gov/pubmed/23263018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31827d413e
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