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SLEEP AND GABA LEVELS IN THE ORAL PART OF RAT PONTINE RETICULAR FORMATION ARE DECREASED BY LOCAL AND SYSTEMIC ADMINISTRATION OF MORPHINE

Morphine, a μ-opioid receptor agonist, is a commonly prescribed treatment for pain. Although highly efficacious, morphine has many unwanted side effects including disruption of sleep and obtundation of wakefulness. One mechanism by which morphine alters sleep and wakefulness may be by modulating GAB...

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Autores principales: Watson, Christopher J., Lydic, Ralph, Baghdoyan, Helen A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729685/
https://ncbi.nlm.nih.gov/pubmed/17055662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2006.09.007
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