Pontine Reticular Formation (PnO) Administration of Hypocretin-1 Increases PnO GABA Levels and Wakefulness

STUDY OBJECTIVES: GABAergic transmission in the oral part of the pontine reticular formation (PnO) increases wakefulness. The hypothalamic peptide hypocretin-1 (orexin A) promotes wakefulness, and the PnO receives hypocretinergic input. The present study tested the hypothesis that PnO administration...

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Hlavní autoři: Watson, Christopher J., Soto-Calderon, Haideliza, Lydic, Ralph, Baghdoyan, Helen A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Associated Professional Sleep Societies, LLC 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279760/
https://ncbi.nlm.nih.gov/pubmed/18457232
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