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Respiratory pathology in the Optn(−/−) mouse model of Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disorder that results in death due to respiratory failure. Many genetic defects are associated with ALS; one such defect is a mutation in the gene encoding optineurin (OPTN). Using an optineurin null mouse (Optn(−/−)), we sought...
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| Publicado no: | Respir Physiol Neurobiol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7530116/ https://ncbi.nlm.nih.gov/pubmed/32805420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2020.103525 |
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