Intralingual Administration of AAVrh10-miR(SOD1) Improves Respiratory But Not Swallowing Function in a Superoxide Dismutase-1 Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by degeneration of motor neurons and muscles, and death is usually a result of impaired respiratory function due to loss of motor neurons that control upper airway muscles and/or the diaphragm. Currently, no cure for ALS exists and...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Lind, Lori A., Andel, Ellyn M., McCall, Angela L., Dhindsa, Justin S., Johnson, Katherine A., Stricklin, Olivia E., Mueller, Christian, ElMallah, Mai K., Lever, Teresa E., Nichols, Nicole L.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462029/
https://ncbi.nlm.nih.gov/pubmed/32498636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2020.065
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