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Identifying Optimal Loci for the Molecular Diagnosis of Microsatellite Instability

BACKGROUND: Microsatellite instability (MSI) predicts oncological response to checkpoint blockade immunotherapies. Although microsatellite mutation is pathognomonic for the condition, loci have unequal diagnostic value for predicting MSI within and across cancer types. METHODS: To better inform mole...

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Bibliografiske detaljer
Udgivet i:Clin Chem
Main Authors: Long, Dustin R, Waalkes, Adam, Panicker, Varun P, Hause, Ronald J, Salipante, Stephen J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528407/
https://ncbi.nlm.nih.gov/pubmed/33001187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/clinchem/hvaa177
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