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Molecular and Computational Methods for the Detection of Microsatellite Instability in Cancer

Microsatellite instability (MSI) is a genomic alteration in which microsatellites, usually of one to four nucleotide repeats, accumulate mutations corresponding to deletions/insertions of a few nucleotides. The MSI phenotype has been extensively characterized in colorectal cancer and is due to a def...

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Dettagli Bibliografici
Pubblicato in:Front Oncol
Autori principali: Baudrin, Laura G., Deleuze, Jean-François, How-Kit, Alexandre
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315116/
https://ncbi.nlm.nih.gov/pubmed/30631754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00621
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